The Science Behind IV Ketamine Therapy for Mental Health
When traditional treatments for depression, anxiety, or trauma don’t provide relief, many patients feel stuck, hopeless, or frustrated. At Sturges Family Practice, we offer IV Ketamine therapy, an evidence-based treatment that has shown remarkable results for individuals with treatment-resistant mental health conditions. But what exactly makes IV Ketamine effective, and how does it work?
Understanding IV Ketamine Therapy
Ketamine has been used safely for decades as an anesthetic, but research over the past 20 years has revealed its powerful effects on mental health at lower doses. IV Ketamine therapy involves the intravenous administration of ketamine in a controlled medical setting, allowing precise dosing and careful monitoring for safety and comfort.
Unlike traditional antidepressants, which may take weeks to show results, IV Ketamine often provides rapid symptom relief, sometimes within hours to days. This can be life-changing for patients struggling with severe depression, anxiety, PTSD, or chronic suicidal thoughts.
How IV Ketamine Works in the Brain
Ketamine works differently from standard antidepressants. Its primary mechanism involves the NMDA receptor, which regulates glutamate, the brain’s most abundant neurotransmitter. By modulating glutamate signaling, ketamine promotes:
Neuroplasticity: The brain’s ability to form new connections, improving mood regulation and cognitive flexibility.
Rapid symptom relief: Often faster than traditional medications, especially for treatment-resistant depression.
Reduction in suicidal thoughts: Studies show ketamine can quickly reduce acute suicidal ideation, giving patients crucial time to stabilize.
Additionally, IV Ketamine appears to reduce inflammation and oxidative stress in the brain, factors that are increasingly recognized as contributors to mood disorders.
Who Can Benefit from IV Ketamine Therapy?
IV Ketamine is particularly helpful for individuals who:
Have not responded to multiple antidepressants or therapy
Experience treatment-resistant depression or anxiety
Struggle with PTSD or trauma-related symptoms
Have acute suicidal thoughts that require rapid intervention
At Sturges Family Practice, we conduct a comprehensive evaluation to ensure IV Ketamine therapy is safe and appropriate for each patient.
What to Expect During Treatment
IV Ketamine is administered in a calm, monitored clinical environment. Each session typically lasts 40–60 minutes, during which patients are closely observed by our trained medical team. Many patients describe feeling a sense of mental clarity, emotional relief, and reduced anxiety during and after treatment.
Treatments are personalized in frequency and dosage based on the patient’s needs, and therapy is often combined with ongoing mental health support, lifestyle strategies, and other personalized interventions to maximize long-term benefits.
The Role of Compassionate Care
At Sturges Family Practice, we understand that mental health recovery is more than just medication. Our team provides compassionate, individualized care, supporting patients through each step of their healing journey. IV Ketamine is just one tool we use to help patients regain hope, resilience, and a renewed sense of possibility.
Your Next Step
If you’ve struggled with depression, anxiety, or trauma despite trying traditional treatments, IV Ketamine therapy may offer the rapid relief you need. Our team at Sturges Family Practice combines innovative therapies with compassionate care to help you feel supported and empowered on your mental health journey.

